Throughout the 10 cycles of America’s Next Top Model, there have a number of girls who weren’t considered typical models. (Who knew tomboy Lauren would look hot with makeup on?) Then there were those with very masculine traits. (Remember when Paulina called Dominique the transvestite version of Robin Wright Penn?)

Now for the show’s eleventh season, the producers will once again be challenging our concept of beauty. For the first time, the series will be introducing its first transgendered contestant. During her interview before the judges’ panel, 22-year-old Isis explained why she chose to transform herself from a man to a woman. “I was born physically male…but mentally, everything else, I was born female.”